I-Nuclear Magnetic Resonance (i-NMR) yi-nuceli (yeNyukliya) ebonakalayo ebonisa ukufikelela kwizicelo kuyo yonke inzululwazi yomzimba, ikhemistri kunye nomzi mveliso. I-NMR isebenzisa umazibuthe omkhulu (iMagnetic) ukuphanda ngeempawu zangaphakathi ezijikelezayo ze-atomic nuclei. Njengazo zonke izinto ezibukwayo, i-NMR isebenzisa icandelo lombane wombane (amaza erediyo) ukukhuthaza utshintsho phakathi kwamanqanaba enyukliya (i-Resonance).

Namhlanje, i-NMR iye yaba yitekhnoloji yokuhlalutya enobunkunkqele nonamandla efumene usetyenziso olwahlukeneyo kwiinkalo ezininzi zophando lwezenzululwazi, amayeza, kunye nemizi-mveliso eyahlukeneyo. I-spectroscopy yeNMR yanamhlanje ibigxininisa usetyenziso kwiinkqubo ze-biomolecular kwaye idlala indima ebalulekileyo kwibhayiloji yolwakhiwo. Ngophuhliso lwendlela zombini kunye nokusetyenziswa kwezixhobo kule minyaka ingamashumi amabini idlulileyo, i-NMR iye yaba yenye yezona ndlela zinamandla kunye neziguquguqukayo zokwenza uhlalutyo lwee-biomacromolecule.

Imagnethi ye-NMR ngokuqinisekileyo yeyona ndawo ibaluleke kakhulu kwisibonisi se-NMR. Imagnethi ye-NMR yenye yezona zinto zibiza kakhulu kwinkqubo yenyukliya yokujonga umbane. Itekhnoloji yomazibuthe yeNMR iguquke kakhulu ukusukela oko kwaphuhliswa i-NMR. Iimagnethi zakuqala ze-NMR bezisisiseko sesinyithi esisigxina okanye ii-electromagnet ezivelisa amandla kazibuthe angaphantsi kwe-1.5 T. Namhlanje, uninzi lweemagnethi ze-NMR ziluhlobo lokuqhuba kakhulu.